Mikhail Blagosklonny argues that rapamycin extends the lifespan, albeit it has limited impacts on aging. According to Mikhail, aging is the exponential increase in death’s probability with age. In his view, no one dies without a cause. Instead, older adults die from diseases that are age-related or natural causes. Not only human beings and mammals die from natural causes but flies and worms that age die from similar pathologies. Moreover, Mikhail says that age-related diseases bio-mark aging with the most common cardiovascular diseases such as Alzheimer, diabetes, hypertension, cancer. However, he notes that many manifestations of aging such as menopause are not considered diseases because they develop in all people.
Mikhail also posits that cellular aging is dependent on the Mechanistic or Mammalian Target of Rapamycin (MTOR). Further, he posits hormones such as testosterone and insulin, growth factors oxygen, nutrients, and conditions like obesity activate the MTOR pathway. MTOR stimulates some particular functions of differentiated cells and mass growth. Also, except for the terminal stages of age-related ailments, aging is associated with hyperfunctions that are systematic. The above hyperfunctions include increased platelet aggregation, increased blood pressure, hypercoagulation, hyperglycemia, hyperinsulinemia, and the growing resistance to hormones. Since these functions are damaging to the organs, they lose some of their regular duties. Rapamycin does not reverse the terminal stages since they are MTOR independent.
Mikhail Blagosklonny is a professor, researcher, philanthropist who is renowned in all sections of the world. He terms himself as an average person who desires to see all individuals in the world receive the best medical care irrespective of their economic stand. Mikhail specializes in the field of aging and cancer and how the two are connected. Specifically, he researches on why cancer is more common in older individuals than in the younger generation. His research is useful in the oncology field, and it is bound to be helpful even in future years. Further, Mikhail inspires his peers and students who would want to continue their career in the field.Mikhail not only focuses on how to treat cancer but how to treat cancer in an efficient manner that is not excruciating and expensive as the present day treatments. He focuses on how the cancer cells can be removed from the body without destroying the healthy body cells that help recover the mind and body cells after many years of suffering from cancer. Mikhail hopes that his findings will inspire other people to continue with his research long after he has left the field. His goal is to see that the cancer treatment is not a luxury treatment for the wealthy but an easy and cost-effective treatment for all people.